Research

Mary Lyon Centre

MRC Harwell Institute is comprised of the Mary Lyon Centre (MLC) and the Mammalian Genetics Unit (MGU) that together function as a multi-disciplinary, integrated campus, funded by the MRC, dedicated to research using the mouse as a model for the study and diagnosis of human disease.

The MLC is a national facility providing world-class expertise, tools and resources to generate and characterise genetically altered mouse models for use by clinical and biomedical scientists. The MLC resources support academic researchers throughout the UK and include genome engineering, advanced phenotyping and cryopreservation. All services are underpinned by quality controlled husbandry and animal care with an emphasis on refinement and reproducibility. 

MRC Harwell Institute is a leading member of the International Mouse Phenotyping Consortium, an extensive group of mouse genetics centres across the world which are striving to ascribe function to every gene in the mouse genome. The MLC also hosts an internationally recognised mouse archive, facilitating third party access to existing and novel models being developed at Harwell and other institutes.

Expert teams of scientists, technicians and animal care staff at the MRC Harwell Institute are bringing technical advances in genetic research, refinements in phenotyping and improvements in animal care to the UK biomedical community.

For further information, please contact MRC Harwell.