Name of Bank |
Newcastle Brain Tissue Resource |
Summary |
To provide well characterised tissue for research into dementia and neurodegenerative diseases particularly non Alzheimer type dementias such as Lewy Body Disease and vascular dementia. |
Primary Contact(s) |
Debbie Lett
Chris Morris |
Available Sample Types |
Approx 1500 cases collected over a period of 30 years originally comprising one snap frozen hemisphere and paraffin embedded tissue as well as tissue in formalin. Due to the time span some of the older cases are already well used. There is some control tissue but this is in high demand. |
Sample Derivatives |
DNA/RNA is available for some cases |
Disease types/subtypes available |
Alzheimers Disease, Lewy Body Disease, Parkinsons Disease (with and without dementia), Frontotemporal dementia, vascular dementia, MND, mitochondrial diseases, depression also collection of neurological and psychiatric rarities. |
Sources of Sample Annotation |
Newer cohorts have full associated clinical and research records, older cases often have limited clinical information available. |
Funding Bodies |
MRC, Biomedical Research Council, Brains for Dementia Research( Funded by AS & ART) |
Additional Information |