Multiple Sclerosis and Parkinson's Tissue
Name of Bank |
Multiple Sclerosis and Parkinson’s Tissue Bank |
Summary |
The bank operates two nationwide prospective donor schemes with a total of approx 9,000 donors. The MSPTB is a valuable source of high quality human CNS samples and has been set up to acquire brain and spinal cord from the entire continuum of multiple sclerosis and Parkinsonian pathologies and to make those samples and associated data available to neuroscientists across the globe in order to facilitate research into these and related neurological conditions. Our collection contains over 100,000 snap-frozen, fixed-frozen/cryoprotected and paraffin-embedded specimens from over 900 clinically and neuropathologically well characterised MS, PD and control cases. The Tissue Bank operates an easy and open access policy to tissue and welcomes applications from academic institutions and the biotechnology and biopharm sector. |
Primary Contact(s) |
Dr Djordje Gveric |
Available Sample Types |
Mainly brain, spinal cord and CSF from multiple sclerosis, Parkinson’s Disease and controls/disease controls. Muscle samples (paraspinal muscle) are available for some of the MS and PD cases. Snap-frozen, cryoprotected (sucrose) and fixed frozen and formalin fixed/paraffin embedded tissue blocks. Aliquots of frozen cerebrospinal fluid. Whole formalin fixed brains and brain slices (MS, PD and controls/disease controls). |
Sample Derivatives |
Currently no derivatives are available. |
Disease types/subtypes available |
MS – primary and secondary progressive and relapsing-remitting forms PD – idiopathic Parkinson’s disease, PD with dementia, multiple systems atrophy, progressive supranuclear palsy, corticobasal degeneration and dementia with Lewy bodies |
Sources of Sample Annotation |
MS: GP and neurology notes including medical history and treatments, MSIS-32 and health questionnaires. Full neuropathology report. PD: GP and neurology notes including medical history and treatments, exhaustive health, lifestyle and follow up questionnaires. Full neuropathology report. |
Funding Bodies |
Multiple Sclerosis Society of Great Britain and Northern Ireland and Parkinson’s UK |
Additional Information |
Multiple Sclerosis - www.ukmstissuebank.imperial.ac.uk Parkinson's - www.parkinsonstissuebank.org.uk |