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Theory goes pear shaped: ‘Apple shape’ no worse for heart

Friday 11 March 2011

 

A new international study funded by the Medical Research Council (MRC) and the British Heart Foundation (BHF) challenges the idea that obese people with an apple shape (fat around the middle of the body) are at higher risk of heart attacks and strokes than obese people with other types of fat distribution.

 

The Emerging Risk Factors Collaboration, a consortium of 200 scientists from 17 countries led by the University of Cambridge, monitored the health of over 220,000 adults for almost a decade. The researchers found that although obesity was clearly a major indicator of heart disease in itself, body mass index (BMI), waist circumference, and waist-to-hip ratio each had a similar impact on the risk of heart attack and strokes. This finding contradicts earlier studies which have suggested that those with ‘central obesity’ (as assessed by the ratio of the waist to hip circumference, or waist-to-hip ratio) have three times greater risk of heart attack than people with general obesity as assessed by BMI.

 

The study reveals that when information on a patient’s blood pressure, history of diabetes and fat levels are available, additional measures of BMI, waist circumference and waist-to-hip ratio do not add to the picture when predicting their risk of developing heart disease.

 

Researchers from the Cardiovascular Epidemiology Unit at the University of Cambridge said:

 

“This study shows that measuring your waist is no better for calculating your cardiovascular risk than calculating your BMI. Excess fat levels remain the main risk factor for heart disease which can of course be influenced by lifestyle choices.

The study highlights the value of GPs continuing to measure cholesterol and blood pressure levels, irrespective of body shape. The findings should help guide medical practice worldwide because national and international guidelines have provided differing recommendations about the value of measures of obesity for prediction of heart disease risk.”

 

Professor Stephen Holgate, chair of the MRC’s Population and Systems Medicine Board, said:

 

“The main concern with obesity is that it leads on to other illnesses. Around 60% of type 2 diabetes and 20% of heart disease cases are attributable to excess body fat. Six cancers are also linked to obesity. MRC scientists have been working on obesity for more than two decades and by funding this kind of gold standard research, we hope to help arm doctors and patients with the best possible evidence to help prevent, diagnose and treat diseases associated with obesity.”

 

MRC Press Office
Press Office number: 020 7395 2456
Email: press.office@headoffice.mrc.ac.uk

  • 1. The study ‘Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies’ is published on Friday, March 11 in the journal The Lancet.
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  • 2. For almost 100 years the Medical Research Council has improved the health of people in the UK and around the world by supporting the highest quality science. The MRC invests in world-class scientists. It has produced 29 Nobel Prize winners and sustains a flourishing environment for internationally recognised research. The MRC focuses on making an impact and provides the financial muscle and scientific expertise behind medical breakthroughs, including one of the first antibiotics penicillin, the structure of DNA and the lethal link between smoking and cancer. Today MRC funded scientists tackle research into the major health challenges of the 21st century. www.mrc.ac.uk.
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  • 3. The British Heart Foundation is the nation’s heart charity, dedicated to saving lives through pioneering research, patient care, campaigning for change and by providing vital information. But we urgently need help. We rely on donations of time and money to continue our life-saving work. Because together we can beat heart disease. For more information visit bhf.org.uk/pressoffice
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  • 4. The University of Cambridge’s mission is to contribute to society through the pursuit of education, learning and research at the highest international levels of excellence. It admits the very best and brightest students, regardless of background, and offers one of the UK’s most generous bursary schemes. The University of Cambridge’s reputation for excellence is known internationally and reflects the scholastic achievements of its academics and students, as well as the world-class original research carried out by its staff. Some of the most significant scientific breakthroughs occurred at the University, including the splitting of the atom, invention of the jet engine and the discoveries of stem cells, plate tectonics, pulsars and the structure of DNA. From Isaac Newton to Stephen Hawking, the University has nurtured some of history’s greatest minds and has produced more Nobel Prize winners than any other UK institution with over 80 laureates.
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    Photo by Josh Liba, available under a Creative Commons Attribution-NonCommercial-NoDerivs 2.0 Generic license

     

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